HomeNews & TopicsResearchPatients with sepsis at higher risk of stroke, heart attack after hospital...

Patients with sepsis at higher risk of stroke, heart attack after hospital discharge

Published on

Patients with sepsis are at increased risk of stroke or myocardial infarction (heart attack) in the first 4 weeks after hospital discharge, according to a large Taiwanese study published in CMAJ (Canadian Medical Association Journal).

Sepsis accounts for an estimated eight million deaths worldwide, and in Canada causes more than half of all deaths from infectious diseases.

Researchers looked at data on more than 1 million people in Taiwan, of whom 42 316 patients had sepsis, matched with control patients in the hospital and the general population. All sepsis patients had at least one organ dysfunction, 35% were in the intensive care unit and 22% died within 30 days of admission. In the total group of patients with sepsis, 1012 had a cardiovascular event, 831 had a stroke and 184 had a myocardial infarction within 180 days of discharge from hospital. Risk was highest in the first 7 days after discharge, with more than one-quarter (26%) of myocardial infarction or stroke occurring in the immediate period and 51% occurring within 35 days.

A North American first: Using a novel technology to perform complex aortic surgery

“We found that within the first 4 weeks after discharge from hospital was the critical period with a markedly elevated risk of [myocardial infarction] and stroke,” writes Dr. Chien-Chang Lee, Department of Emergency Medicine, National Taiwan University Hospital, Taipei, Taiwan, with coauthors.

The authors also found that younger patients with sepsis aged 20 to 45 years were at higher risk of heart attack or stroke compared to patients over age 75.

This study extends the findings of a Danish study that reported similar trends.

“Based on our study (Han Chinese) and the study in Denmark (European) that reported similar findings for two different ethnic groups, it is likely that these results are generalizable to different populations,” write the authors.

They call for further validation of their findings in different populations.

“Susceptible period for cardiovascular complications in patients recovering from sepsis” is published September 10, 2018.

Latest articles

An ER doctor’s experience with long COVID – “My symptoms seemed endless”

On April 2022, another COVID wave was sweeping Toronto. It was the sixth since...

Tackling the issue of unused medication waste

When patients and programs don’t use all the medication that is prescribed, it is...

Obesity a risk factor for stillbirth, especially at term

Obesity is a risk factor for stillbirth, and the risk increases as pregnancy advances...

Prolonged cough? In most cases, patience is the treatment

Coughing after a respiratory infection is common and, in most cases, will resolve with...

More like this

Obesity a risk factor for stillbirth, especially at term

Obesity is a risk factor for stillbirth, and the risk increases as pregnancy advances...

Navigating the fallout: 23andMe’s data breach and the ethics of consumer genetic testing

By unlocking secrets encrypted within our DNA, genetic testing has become a powerful tool,...

Researching a new treatment for sepsis

For people who are in the intensive care unit (ICU) with a serious health...

Health care inequities behind shorter life spans for Inuit from Nunavik, Quebec, with lung cancer

People living in the Inuit region of Nunavik in northern Quebec die earlier after...

Polycystic ovarian syndrome: new review to help diagnose and manage

A new review in CMAJ (Canadian Medical Association Journal) is aimed at helping clinicians...

Organ donations after MAiD made up 14 per cent of deceased donations in Quebec

Organ donation after medical assistance in dying (MAiD) represented 14 per cent of Quebec's...