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Pulmonary and Respirology

UHN surgeons curing rare lung condition CTEPH with world-class procedure

HN Summary • UHN surgeons are curing a rare and potentially fatal lung condition, CTEPH, using one of the world’s most advanced surgical procedures — pulmonary thromboendarterectomy (PTE) — which removes chronic blood clots from even the smallest pulmonary vessels. UHN operates the largest and...

Young men who vape may be at greater risk for future heart disease

E-cigarettes, commonly known as vapes, contain nicotine and various chemicals, including some used for flavourings, which make them more attractive to young people. Despite measures to protect youth, such as age restrictions and flavour bans, all types of vaping products remain easily available online....

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Wildfire smoke and health

With wildfires becoming more frequent and extensive in Canada, it’s important for people to...

Vaping additives harm a vital membrane in the lungs, according to new Concordia research

Vitamin E binds itself to the pulmonary surfactant, inhibiting gas exchange and lung stability The...

World-first trial shows benefits of finding, treating undiagnosed asthma and COPD

It’s estimated that 70 per cent of people with asthma or COPD go undiagnosed....

Conquering a chronic lung infection

Lung problems plagued David Shoots since his youth. It would take buying a dream...

How frailty can impact lung disease

A new study from UHN’s Toronto General Hospital Research Institute (TGHRI) has identified the...

1000th Ex-Vivo Lung Perfusion transplantation surgery celebrated at UHN

Shaf Keshavjee and Marcelo Cypel continue to see the future for the Ex-Vivo Lung...

Breathing deep: The environmental impact of inhalers

Canada is caught in a vicious cycle when it comes to maintaining respiratory health...

Air filter rebates for people in BC with asthma?

The rising number and intensity of wildfires in British Columbia are taking an immense...

Prolonged cough? In most cases, patience is the treatment

Coughing after a respiratory infection is common and, in most cases, will resolve with...

Tiny trailblazer: First baby treated in world-first trial for chronic lung disease

At two weeks old, Emerson Cogan was already a pioneer. Born February 20, 2023, at...

Life-support system reduced COVID-19 mortality by 7.1 per cent, study shows

A new study published in the British Medical Journal (BMJ), led by UHN researchers and the...

Breath monitoring improves patient safety during endoscopy unit procedures in pilot project

By Mae Burke and Cheryl Ha A pilot project in the Therapeutic Endoscopy Unit at...

Latest articles

New approach opens door to better-targeted treatments and faster drug discovery for complex diseases

McGill researchers have developed an AI tool called SIDISH that identifies high-risk cancer cells driving aggressive disease, enabling more precise and targeted treatment strategies. By linking single-cell data with patient outcomes, the tool can predict disease progression and simulate responses to potential drug targets, helping accelerate drug discovery and repurposing. While still in development, SIDISH shows promise for advancing personalized cancer care and improving outcomes across multiple tumour types.

Canadian Cancer Society urges lowering colorectal cancer screening age to 45

The Canadian Cancer Society is urging provinces to lower the colorectal cancer screening age from 50 to 45, citing rising rates among younger adults and evidence that earlier screening could prevent over 15,000 cases and 6,100 deaths. Younger patients are more often diagnosed at advanced stages, making early detection critical. Expanding access to simple screening tools like FIT tests could significantly improve outcomes and save lives.

Unleashing natural killer cells against cancer

Researchers at McGill University have developed a new strategy to enhance natural killer (NK) cells, enabling them to better penetrate tumour defenses and destroy cancer cells. Using small-molecule drugs to temporarily boost NK cell activity—rather than permanent genetic modification—the approach showed strong results against multiple hard-to-treat cancers in preclinical studies. The scalable, ready-to-use therapy could make immunotherapy faster, safer, and more accessible, with future clinical trials planned for aggressive cancers like acute myeloid leukemia.

Doctors report false health information, lack of health data sharing put patient care at risk

A new CMA survey reveals major risks to patient care in Canada, with 99% of physicians reporting that disconnected health systems limit access to critical patient information and nearly half witnessing serious adverse outcomes as a result. At the same time, 97% of doctors say they have intervened to address harm caused by false or misleading online health information, including AI-generated advice. The findings highlight the urgent need for integrated digital health systems and stronger efforts to promote reliable health information.